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ODM-203|31451-5 mg|CAS:1430723-35-5

产品编号

31451-5 mg

英文名称

ODM-203

标准价

~~¥ 1795.6~~

优惠价

¥ 1795.6

CAS号

1430723-35-5

规格

5 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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ODM-203介绍：

产品名称:

ODM-203

产品描述:

A dual inhibitor of VEGFR and FGFR (IC50s = 5-26 and 6-35 nM for VEGFR1-3 and FGFR1-4, respectively); selective for VEGFR1-3 and FGFR1-4 over a panel of 308 kinases at 1 µM; inhibits PDGFRα, PDGFRβ, and DDR1 (IC50s = 35, 169, and 6 nM, respectively), as well as MAP4K4, MINK1, RET, SIK2, YES1, and Tie2 (IC50s = 49, 41, 8, 23, 152, and 174 nM, respectively; inhibits FGFR-dependent proliferation in H1581 lung, SNU-16 stomach, and RT4 bladder cancer cells (IC50s = 104, 132, and 192 nM, respectively) and VEGF-induced tube formation by HUVECs (IC50 = 33 nM); decreases tumor volume in a RT4 mouse xenograft model at 20 and 40 mg/kg; reduces tumor growth and intratumor phosphorylation of FGFR in a SNU-16 mouse xenograft model at 30 mg/kg

保存温度:

-20

运输温度:

-20

预期分子量:

505.540246

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥98%

CAS号:

1430723-35-5

分子式:

C26H21F2N5O2S

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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