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R1487 (hydrochloride)|31478-1 mg|CAS:449808-64-4
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R1487 (hydrochloride)|31478-1 mg|CAS:449808-64-4

31478-1 mg
R1487 (hydrochloride)
¥ 549.4
¥ 549.4
1 mg
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R1487 (hydrochloride)介绍:

产品名称:
R1487 (hydrochloride)
产品描述:
An inhibitor of p38α MAPK (IC50 = 10 nM); selective for p38α over p38β MAPK (Kds = 0.2 and 29 nM, respectively), as well as a panel of 306 additional kinases at 10 µM, but does inhibit 11 kinases by >85% at 10 µM; inhibits LPS-induced IL-1β production in isolated human whole blood (IC50 = 170 nM); inhibits LPS-induced production of TNF-α and IL-6 in rats (ED50s = 0.8 and 0.4 mg/kg); reduces yeast-induced hyperalgesia in rats (ED50 = 5.5 mg/kg)
保存温度:
-20
运输温度:
-20
预期分子量:
388.368186
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
449808-64-4
分子式:
C19H18F2N4O3 • HCl

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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