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DS-1001b|31488-1 mg|CAS:1898207-64-1
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DS-1001b|31488-1 mg|CAS:1898207-64-1

31488-1 mg
DS-1001b
¥ 844.2
¥ 844.2
1898207-64-1
1 mg
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DS-1001b介绍：

产品名称:
DS-1001b
产品描述:
An inhibitor of mutant IDH1 (IC50s = 15 and 130 nM for IDH1R132H and IDH1R132C, respectively); selective for mutant IDH1 over wild-type IDH1 and IDH2, as well as IDH2R140Q and IDH2R172Q (IC50s = >10,000 nM for all); inhibits 2-HG production in TF-1 cells stably transfected with IDH1R132H or IDH1R132C (IC50s = 29 and 35 nM, respectively) and in 293A cells transiently transfected with IDH1R132H or IDH1R132C (IC50s = 29 and 42 nM, respectively); reduces tumor growth, as well as intratumoral and plasma 2-HG levels, in a subcutaneous IDH1R132H-expressing A1074 PDX mouse model of glioblastoma
保存温度:
-20
运输温度:
-20
预期分子量:
535.778003
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1898207-64-1
分子式:
C25H18Cl3FN2O4 • C4H11N

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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