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MPI-0479605|44704-1 mg|CAS:1246529-32-7
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MPI-0479605|44704-1 mg|CAS:1246529-32-7

44704-1 mg
MPI-0479605
¥ 335.0
¥ 335.0
1 mg
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MPI-0479605介绍:

产品名称:
MPI-0479605
产品描述:
An Mps1 inhibitor (IC50 = 1.8 nM); selective for Mps1 over a panel of 79 kinases at 500 nM; induces time-dependent degradation of cyclin B and securin and decreases phosphorylation of Mad3, resulting in failed cytokinesis in nocodazole-arrested HeLa cells; induces cell cycle arrest at the G2/M phase in HCT116 cells, which express p53wt, and COLO 205 cells, which express p53mut, at 1 µM; reduces tumor volume in an HCT116 mouse xenograft model at 30 to 150 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
407.522
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
1246529-32-7
分子式:
C22H29N7O

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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