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(R)-STU104|45375-1 mg|CAS:2767124-77-4
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(R)-STU104|45375-1 mg|CAS:2767124-77-4

45375-1 mg
(R)-STU104
¥ 656.6
¥ 656.6
1 mg
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(R)-STU104介绍:

产品名称:
(R)-STU104
产品描述:
An inhibitor of the TAK1-MKK3 protein-protein interaction; binds MKK3 (KD = 71 nM), inhibits the phosphorylation of MKK3 in RAW 264.7 macrophages (IC50 = 4 µM), and disrupts the interaction between MKK3 and TAK1 in the same cells; reduces TNF-α levels (IC50 = 0.58 µM) and p38 and eIF4E phosphorylation in LPS-stimulated RAW 264.7 macrophages; increases body weight and colon length and reduces serum levels of TNF-α, IL-1β, IL-6, and IL-23 in mouse model of ulcerative colitis induced by DSS; increases the survival rate in an IL-10-/- knockout mouse model of chronic ulcerative colitis
保存温度:
-20
运输温度:
-20
预期分子量:
298.338
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2767124-77-4
分子式:
C18H18O4

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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