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Tracazolate|45457-1 mg|CAS:41094-88-6
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Tracazolate|45457-1 mg|CAS:41094-88-6

45457-1 mg
Tracazolate|45457-1 mg|CAS:41094-88-6
¥ 1326.6
¥ 1326.6
1 mg
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Tracazolate介绍:

产品名称:
Tracazolate
别名:
ICI 136753
产品描述:
A positive allosteric modulator of the GABAA receptor; potentiates GABA-stimulated currents in X. laevis oocytes expressing α1β3γ2s and α1β1δ subunit-containing GABAARs (EC50s = 1.5 and 16.7 µM, respectively) and increases the maximal response to GABA in X. laevis oocytes expressing α1β1δ subunit-containing GABAARs, but reduces the maximal response to GABA in X. laevis oocytes expressing α1β3γ2s subunit-containing GABAARs; selectively potentiates GABA-induced currents in X. laevis oocytes expressing β3 over β1 subunit-containing GABAARs (EC50s = 1.5 and 13.2 µM for α1β3γ2s and α1β1γ2s subunit-containing GABAARs, respectively); increases time spent in social interactions but does not reduce locomotor activity, indicating anxiolytic but not sedating activity, in rats at 5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
304.394
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
41094-88-6
分子式:
C16H24N4O2

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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