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TTA-A2|42236-5 mg|CAS:953778-63-7
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TTA-A2|42236-5 mg|CAS:953778-63-7

42236-5 mg
TTA-A2
¥ 4113.8
¥ 4113.8
5 mg
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TTA-A2介绍:

产品名称:
TTA-A2
产品描述:
A T-type calcium channel inhibitor (IC50s = 89, 92, and 98 nM for Cav3.1, Cav3.2, and Cav3.3, respectively, in patch-clamp assays at -80 mV); selective for these channels over Cav1.2, Cav2.1, Cav2.2, and Cav2.3 in patch-clamp assays (IC50s = >30 µM for all at -90 mV); reduces the viability of spheroid A549 lung cancer cells at 100 or 200 nM; decreases body weight gain and fat mass and increases lean muscle mass in mice fed a high-fat diet; inhibits amphetamine- or MK-801-induced locomotor activity in rats at 3 mg/kg; decreases the mean time spent in active wake and REM sleep and increases the mean time spent in delta sleep in wild-type but not Cacna1g-/- and Cacna1i-/- double knockout mice when administered one hour before the inactive phase at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
378.388229
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
953778-63-7
分子式:
C20H21F3N2O2

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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