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ZD 4190|42248-1 mg|CAS:413599-62-9

产品编号

42248-1 mg

英文名称

ZD 4190

标准价

~~¥ 723.6~~

优惠价

¥ 723.6

CAS号

413599-62-9

规格

1 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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ZD 4190介绍：

产品名称:

ZD 4190

产品描述:

A VEGFR1, VEGFR2, and EGFR inhibitor (IC50s = 0.7, 0.03, and 0.4 µM, respectively); selective for these kinases over PDGFRβ, FGFR1, and HER2 (IC50s = 3.4, >100, and >100 µM, respectively) and MEK, Cdk2, IGF-1R, Akt, and Tie2 (IC50s = >10, >10, >20, >20, and >100 µM, respectively); selectively inhibits VEGF- or EGF-induced proliferation of HUVECs over FGF-induced proliferation of HUVECs (IC50s = 0.05, 0.05, and 1.5 µM, respectively); reduces tumor volume in a Calu-6 NSCLC mouse xenograft model at 100 mg/kg; inhibits training-induced increases in collateral blood flow and white gastrocnemius muscle capillarity in exercise-trained rats

保存温度:

-20

运输温度:

-20

预期分子量:

459.271983

产品形式:

A solid

有效期:

1460

纯度:

≥98%

CAS号:

413599-62-9

分子式:

C19H16BrFN6O2

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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