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JNJ-10191584 (maleate)|42265-10 mg|CAS:869497-75-6
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JNJ-10191584 (maleate)|42265-10 mg|CAS:869497-75-6

42265-10 mg
JNJ-10191584 (maleate)
¥ 1433.8
¥ 1433.8
10 mg
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JNJ-10191584 (maleate)介绍:

产品名称:
JNJ-10191584 (maleate)
别名:
VUF 6002
产品描述:
A histamine H4 receptor antagonist (Ki = 79.42 nM); selective for the histamine H4 receptor over the histamine H3 receptor (Ki = 3,981 nM); inhibits eosinophil and mast cell chemotaxis (IC50s = 530 and 138 nM, respectively); decreases colonic injury in a rat model of TNBS-induced colitis at 30 and 100 mg/kg and reduces colonic mucosal and submucosal thickness at 100 mg/kg in the same model; reduces the percentage of Th1, Th9, Th17, and regulatory T cells in the spleen, the expression of a variety of cytokines, including Ifng, Il9, and Tgfb1, in the brain, and the development of EAE in mice at 6 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
278.73726
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
869497-75-6
分子式:
C13H15ClN4O • C4H4O4

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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