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APY0201|9001589-1 mg|CAS:1232221-74-7

产品编号

9001589-1 mg

英文名称

APY0201

标准价

~~¥ 549.4~~

优惠价

¥ 549.4

CAS号

1232221-74-7

规格

1 mg

有效期

品牌

萘析精选

标准值

见详情

数量

− +

库存

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APY0201介绍：

产品名称:

APY0201

产品描述:

An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for PIKFYVE over a panel of 137 G protein-coupled receptors, enzymes, ion channels, and transporters, and other kinases only exhibiting >50% inhibition at LOK and ITPK1 at a concentration of 300 nM; inhibits Il-12p70 production ex vivo in murine plasma and reduces colonic inflammation in a mouse Il-10-/- cell transfer model of inflammatory bowel disease in a dose-dependent manner

保存温度:

-20

运输温度:

-20

预期分子量:

413.5

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥98%

CAS号:

1232221-74-7

分子式:

C23H23N7O

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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