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LY294002|70920-5 mg|CAS:154447-36-6
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LY294002|70920-5 mg|CAS:154447-36-6

70920-5 mg
LY294002
¥ 415.4
¥ 415.4
154447-36-6
5 mg
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LY294002介绍：

产品名称:
LY294002
别名:
NSC 697286
产品描述:
A multi-kinase inhibitor; inhibits CK2 (IC50 = 0.098 µM), the PI3K subunits p110α, p110β, p110δ, and p110γ (IC50s = 0.497, 0.554, 0.331, and 3.8 µM, respectively), and DNA-PK (IC50 = 6 µM), among other kinases, as well as CK1, GSK3α, and GSK3β by greater than 40% at 10 µM; inhibits LPS-induced activation of NF-κB in a reporter assay using RAW 264.7 macrophages at 20 µM; induces apoptosis and autophagy in SGC-7901 cells at 50 µM; reduces tumor volume in DLD-1 and LoVo mouse xenograft models at 2 ng/ml/kg; reduces aging-induced increases in the number of aging SA-β-gal-positive human VSMCs at 20 µM in the 5th to 15th generations
保存温度:
-20
运输温度:
-20
预期分子量:
307.3
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
154447-36-6
分子式:
C19H17NO3

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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