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Mizolastine|9000566-250 mg|CAS:108612-45-9
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Mizolastine|9000566-250 mg|CAS:108612-45-9

9000566-250 mg
Mizolastine
¥ 924.6
¥ 924.6
250 mg
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Mizolastine介绍:

产品名称:
Mizolastine
别名:
SL 850324
产品描述:
A histamine H1 receptor antagonist (Ki = 0.001 µM); selective for histamine H1 over histamine H2 and H3 receptors (Kis = >100 µM for both), as well as 5-HT1A , 5-HT1B, 5-HT1C, 5-HT1D, 5-HT2, and 5-HT3, dopamine D1 and D2, α1- and α2-adrenergic, adenosine, and muscarinic receptors in radioligand binding assays (Kis = >1 µM for all); reduces histamine release from bronchial mast cells in ovalbumin-sensitized guinea pigs at 0.1, 0.3, and 1 mg/kg; reduces histamine-induced paw edema in rats, skin edema in dogs, and bronchoconstriction in guinea pigs (ED50s = 0.5, 0.07, and 0.03 mg/kg, respectively); inhibits passive cutaneous anaphylaxis, as well as compound 48/80-induced lethal shock in rats (ED50s = 1.6 and 0.07 mg/kg, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
432.493543
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
108612-45-9
分子式:
C24H25FN6O

本公司销售的所有产品仅供实验科研使用,不用于人体及临床诊断。

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