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MCC950 (sodium salt)|34762-1 mg|CAS:256373-96-3
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MCC950 (sodium salt)|34762-1 mg|CAS:256373-96-3

34762-1 mg
MCC950 (sodium salt)
¥ 428.8
¥ 428.8
256373-96-3
1 mg
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MCC950 (sodium salt)介绍：

产品名称:
MCC950 (sodium salt)
别名:
CP 456,773
产品描述:
An inhibitor of NLRP3 inflammasome activation; inhibits ATP-induced IL-1β release in LPS-primed mouse BMDMs (IC50 = 7.5 nM), as well as cytosolic LPS-induced IL-1β release in Pam3CSK4-primed mouse BMDMs at 0.1 and 1 µM; selective for NLRP3 over NLRC4 and AIM2 inflammasomes and does not inhibit LPS-induced NLRP3 priming in mouse BMDMs at 10 µM; reduces ox-LDL-induced increases in caspase-1 activity and inhibits pyroptosis in THP-1 macrophages at 1 µM; reduces myocardial fibrosis in mice following myocardial infarction induced by left coronary artery ligation at 10 mg/kg; improves forelimb grip strength and reduces spinal edema in a mouse model of spinal crush injury at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
403.4731
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
256373-96-3
分子式:
C20H23N2O5S • Na

本公司销售的所有产品仅供实验科研使用，不用于人体及临床诊断。

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